Peer Reviewed Journal
2025, Vol. 5, Issue 1, Part A
Understanding and progress in the design of buccal mucoadhesive tablets
Author(s): Naina, Sukhchain Kaur, Sukhpreet Kaur, Sumanpreet Kaur and Sukhchain Kaur
Abstract: Buccal tablets are a specialized drug delivery system designed for administration via the buccal mucosa, allowing for systemic drug absorption while bypassing first-pass metabolism. These tablets are formulated to adhere to the buccal cavity, ensuring prolonged drug release and enhanced bioavailability. Excipients such as mucoadhesive polymers, permeation enhancers, and bioadhesive agents play a crucial role in their formulation. Buccal tablets offer several advantages, including improved patient compliance, reduced dosing frequency, and avoidance of gastrointestinal degradation. However, challenges include maintaining adhesion, drug stability, and potential irritation at the application site. The formulation of buccal tablets requires careful selection of excipients to achieve optimal drug release and mucosal permeability. Recent advancements focus on novel polymers and nanotechnology-based approaches to enhance drug delivery efficiency. Buccal tablets are widely used for drugs with poor oral bioavailability, making them a promising alternative for systemic drug administration [1, 2].
Pages: 14-17 | Views: 82 | Downloads: 51
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How to cite this article:
Naina, Sukhchain Kaur, Sukhpreet Kaur, Sumanpreet Kaur, Sukhchain Kaur. Understanding and progress in the design of buccal mucoadhesive tablets. Nat J Pharm Sci 2025;5(1):14-17.
