2024, Vol. 4, Issue 2, Part B
Exploring the role of berberine as anti-cancer agent in cervical cancer
Author(s): Brunda M, Mutthuraj D and Dr. Kanthesh M Basalingappa
Abstract: Berberine is one of the natural alkaloids that is extracted from various medicinal plants and possesses multiple bioactivities including antioxidant, anti-inflammatory, anticancer, and antimicrobial. The traditional use of Berberine has received scientific interest due to its possible treatment options in various diseases, most notably in cancers. This review mainly focuses on cervical cancer which is a frequently reported cancer among women, particularly in the developing country, and HPV is a leading cause. Even though HPV vaccines and screening interventions exist, cervical cancer continues to be a global threat that affects women. In present-day treatment, options like surgery, chemo and radiation are normally associated with various adverse impacts on the patient and are not very effective, especially in the advanced stages of the illness. Berberine possesses a promising anticancer effect on cervical cancer cells. Berberine is reported to play several mechanisms towards anticancer effects on cervical cancer cells including apoptosis, cell growth inhibition and inhibiting signalling pathway and it gives promises a plant-based therapeutic option to boost the effectiveness of current treatments.
Pages: 112-117 | Views: 66 | Downloads: 39
Download Full Article: Click Here
How to cite this article:
Brunda M, Mutthuraj D, Dr. Kanthesh M Basalingappa. Exploring the role of berberine as anti-cancer agent in cervical cancer. Nat J Pharm Sci 2024;4(2):112-117.
