2024, Vol. 4, Issue 1, Part A
Formulation and in vivo assessment of nanocrystal suspensions for parenteral delivery of hydrophobic drugs
Author(s): Shiying Lin
Abstract: The parenteral delivery of hydrophobic drugs poses significant challenges due to poor solubility and bioavailability. Nanocrystal suspensions have emerged as a promising solution to enhance the delivery and efficacy of these drugs. This study aims to develop and evaluate nanocrystal suspensions for the parenteral delivery of hydrophobic drugs. Using a model hydrophobic drug, we formulated nanocrystals via a top-down approach, characterized their physicochemical properties, and assessed their in vivo performance in animal models. The results demonstrated improved solubility, bioavailability, and therapeutic efficacy, highlighting the potential of nanocrystal suspensions as a viable strategy for the parenteral administration of hydrophobic drugs.
Pages: 51-52 | Views: 358 | Downloads: 120
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How to cite this article:
Shiying Lin. Formulation and in vivo assessment of nanocrystal suspensions for parenteral delivery of hydrophobic drugs. Nat J Pharm Sci 2024;4(1):51-52.