2023, Vol. 3, Issue 1, Part B
Role of plant based natural antioxidents on chronic kidney disease
Author(s): SP Srinivas Nayak, Rizwan A Bhaijamal, Jitendra Vaghasia and Shivani R
Abstract: Chronic kidney disease (CKD) is a prevalent global health issue that can lead to end-stage kidney disease and increased risk of cardiovascular disease. CKD is characterized by the progressive impairment of kidney function, which necessitates the exploration of novel therapeutic interventions. This article presents a comprehensive review of the current literature on the potential benefits of antioxidants in CKD patients, as well as the limitations and potential risks associated with antioxidant supplementation. Antioxidants are compounds known for their ability to neutralize free radicals and combat oxidative stress, a common occurrence in CKD. Research has shown that antioxidants hold promise in ameliorating CKD progression and associated complications. Neem, a traditional medicinal plant, has demonstrated improvements in kidney function in animal models with CKD. Bacopa monniera extract, another plant-derived compound, has shown potential in reducing oxidative stress and improving renal function in both animal models and human subjects with CKD. Furthermore, numerous other plants, foods, and spices, including Beta vulgaris, Camellia sinensis, Turmeric, Tulsi (Holy basil), Ginger, and Plums, possess antioxidant and anti-inflammatory properties that may benefit CKD patients. However, it is important to note that some studies have reported no significant effects of antioxidants in CKD patients. Additionally, the benefits of plant-based antioxidants appear to be more pronounced in the prevention of CKD rather than in the treatment of established CKD. While the potential benefits of antioxidants in CKD management are promising, more extensive research is necessary to fully understand their mechanisms of action and therapeutic potential and to establish the efficacy, optimal dosage, and long-term safety of antioxidant interventions in CKD patients.
Pages: 101-106 | Views: 172 | Downloads: 61
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How to cite this article:
SP Srinivas Nayak, Rizwan A Bhaijamal, Jitendra Vaghasia, Shivani R. Role of plant based natural antioxidents on chronic kidney disease. Nat J Pharm Sci 2023;3(1):101-106. DOI: 10.22271/27889262.2023.v3.i1b.74