National Journal of Pharmaceutical Sciences
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P-ISSN: 2788-9262, E-ISSN: 2788-9270

National Journal of Pharmaceutical Sciences


2023, Vol. 3, Issue 1, Part A
Synthesis of 1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro phenyl)-1-oxo-2,3-epoxy propane derivatives as antimicrobial agents


Author(s): Awinash S Chavan

Abstract: Epoxides are the natural phytoconstituents with several biological significance such as Anti-inflammatory, Antioxidant, Anticancer and Antimicrobial activity. The Series 1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro phenyl)-1-oxo-2,3-epoxy propane derivatives was designed and synthesized from 1-(5-chloro-2-hydroxyphenyl)-3-(2-chlorophenyl)-prop-2-en-1-one. Current research work screened for iv vitro anti-bacterial activity against Escherichia coli, Staphylococcus aureus (Pathogens obtained from animal), Xanthomonas citri and Xanthomonas malvacearum (Pathogens obtained from plant). The compound SAC-3 and SAC-6 shows good antibacterial activity while other shows moderate to good anti-microbial activity.

Pages: 20-23 | Views: 22 | Downloads: 11

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How to cite this article:
Awinash S Chavan. Synthesis of 1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro phenyl)-1-oxo-2,3-epoxy propane derivatives as antimicrobial agents. Nat J Pharm Sci 2023;3(1):20-23.


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