2022, Vol. 2, Issue 2, Part B
Nanoemulsion: Methods and application in drug delivery
Author(s): Sakshi Patel, Dr. Jigar Vyas and Dr. Umesh Upadhyay
Abstract: The current study's objective is to create and develop an Econazole nitrate nanoemulsion as a successful therapy for the fungus illness tinea versicolor. An imidazole antifungal with broad range action is econazole nitrate. It is a medication that is low soluble and highly permeable, or BCS class II. After oral administration, it is only partially absorbed due to its weak solubility, and bioavailability varies across people. The drug's topical formulation may be limited in its efficacy due to its weak solubility in the vehicle and low penetration. As a result, nanoemulsions were developed to address these problems. Water nanoemulsions are made using the spontaneous emulsification method. The Franz diffusion cell was used to evaluate the stability, appearance, pH, FTIR, viscosity, drug content, and drug entrapment effectiveness of the nanoemulsion formulations that had withstood thermal stability tests.
Pages: 134-147 | Views: 369 | Downloads: 206
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How to cite this article:
Sakshi Patel, Dr. Jigar Vyas, Dr. Umesh Upadhyay. Nanoemulsion: Methods and application in drug delivery. Nat J Pharm Sci 2022;2(2):134-147.