National Journal of Pharmaceutical Sciences
2022, Vol. 2, Issue 2, Part A
A review article on solubility enhancement
Author(s): Khushi Brahmbhatt, Dr. Jitedra Patel and Dr. Umesh Upadhyaya
Abstract: A key concern in both formulation research and screening studies of new chemical entities has been the solubility of poorly soluble medications. Poor water solubility can limit medication efficacy, and certain pharmaceuticals can exhibit negative effects as a result of their poor solubility. There are various methods used to increase a substance's solubility in water. Therefore, the ability to increase water solubility can be a valuable aid in boosting effectiveness or lowering negative effects for some medications. For solutions delivered topically, orally, or by a parent, this is literal. It is a difficult challenge for pharmaceutical researchers to use the solubility attribute in bioavailability, pharmacology action, and solubility augmentation of various poorly soluble substances. One method for increasing solubility is hydrotropy or hydrotropic solubilization.
Pages: 84-90 | Views: 84 | Downloads: 53
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How to cite this article:
Khushi Brahmbhatt, Dr. Jitedra Patel, Dr. Umesh Upadhyaya. A review article on solubility enhancement. Nat J Pharm Sci 2022;2(2):84-90.