National Journal of Pharmaceutical Sciences
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P-ISSN: 2788-9262, E-ISSN: 2788-9270

National Journal of Pharmaceutical Sciences


2022, Vol. 2, Issue 2, Part A
Metformin: A magic bullet for diabetic world


Author(s): Patel Shivam, Nensi Raytthatha and Umesh Upadhyay

Abstract: The first-line oral blood glucose-lowering medication for type 2 diabetes management is now metformin. Gazlega officinalis, a European herbal remedy discovered to be high in guanidine and demonstrated to decrease blood glucose in 1918, is tied to the history of this plant. After extensive testing, metformin was approved for use in the USA in 1995. Its capacity to combat insulin resistance and treat adult-onset hyperglycemia without weight gain or an increased risk of hypoglycemia gradually gained acceptance in Europe. The UK Prospective Diabetes Study discovered long-term cardiovascular advantages of metformin in 1998, offering a new justification to use metformin as the first line of treatment to control hyperglycemia in type 2 diabetes. After being used to treat diabetes for 60 years, metformin has developed into the most often prescribed medication in the world for decreasing blood sugar, with potential for additional therapeutic uses.

Pages: 63-69 | Views: 34 | Downloads: 11

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How to cite this article:
Patel Shivam, Nensi Raytthatha, Umesh Upadhyay. Metformin: A magic bullet for diabetic world. Nat J Pharm Sci 2022;2(2):63-69.


National Journal of Pharmaceutical Sciences